Sir proteins impede, but do not prevent, access to silent chromatin in living Saccharomyces cerevisiae
Abstract Gene silencing at the mating-type loci in budding yeast (HMRa and HMLα) depends on the Sir proteins. Sir2, Sir3 and Sir4 are indispensable, whereas Sir1 has a limited role. Sir proteins are also involved in repression at telomeres and rDNA repeats. Sir proteins may mediate silencing by limi...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Portfolio
2026-04-01
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| Series: | Scientific Reports |
| Assuntos: | |
| Acceso en liña: | https://doi.org/10.1038/s41598-026-44518-0 |
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