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Common genetic variants, acting additively, are a major source of risk for autism

<p>Abstract</p> <p>Background</p> <p>Autism spectrum disorders (ASD) are early onset neurodevelopmental syndromes typified by impairments in reciprocal social interaction and communication, accompanied by restricted and repetitive behaviors. While rare and especially de novo genetic variation are kn...

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Autori principali: Klei Lambertus, Sanders Stephan J, Murtha Michael T, Hus Vanessa, Lowe Jennifer K, Willsey A, Moreno-De-Luca Daniel, Yu Timothy W, Fombonne Eric, Geschwind Daniel, Grice Dorothy E, Ledbetter David H, Lord Catherine, Mane Shrikant M, Martin Christa, Martin Donna M, Morrow Eric M, Walsh Christopher A, Melhem Nadine M, Chaste Pauline, Sutcliffe James S, State Matthew W, Cook Edwin H, Roeder Kathryn, Devlin Bernie
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2012-10-01
Serie:Molecular Autism
Soggetti:
Narrow-sense heritability
Multiplex
Simplex
Quantitative genetics
Accesso online:http://www.molecularautism.com/content/3/1/9
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