Synergistic activity of caspofungin and posaconazole against Candida (Candidozyma) auris biofilms based on phenotypic, transcriptomic, and in vivo insights

ABSTRACT Candida (Candidozyma) auris is an emerging multidrug-resistant fungal pathogen capable of establishing persistent skin colonization, contaminating the environment, and causing nosocomial outbreaks associated with high mortality rates. Conventional monotherapy frequently proves inadequate ag...

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Detalhes bibliográficos

Principais autores:	Fruzsina Kovács, Andrea Harmath, Dávid Balázsi, Lajos Forgács, Ágota Ragyák, Noémi Balla, Zoltán Tóth, Aliz Bozó, Andrew M. Borman, László Majoros, Renátó Kovács, Ágnes Jakab
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2026-04-01
coleção:	Microbiology Spectrum
Assuntos:	Candida auris transcriptome posaconazole caspofungin echinocandin antifungal therapy
Acesso em linha:	https://journals.asm.org/doi/10.1128/spectrum.02686-25
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