Synergistic activity of caspofungin and posaconazole against Candida (Candidozyma) auris biofilms based on phenotypic, transcriptomic, and in vivo insights

ABSTRACT Candida (Candidozyma) auris is an emerging multidrug-resistant fungal pathogen capable of establishing persistent skin colonization, contaminating the environment, and causing nosocomial outbreaks associated with high mortality rates. Conventional monotherapy frequently proves inadequate ag...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Fruzsina Kovács, Andrea Harmath, Dávid Balázsi, Lajos Forgács, Ágota Ragyák, Noémi Balla, Zoltán Tóth, Aliz Bozó, Andrew M. Borman, László Majoros, Renátó Kovács, Ágnes Jakab
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology 2026-04-01
Serie:	Microbiology Spectrum
Soggetti:	Candida auris transcriptome posaconazole caspofungin echinocandin antifungal therapy
Accesso online:	https://journals.asm.org/doi/10.1128/spectrum.02686-25
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!