Genome‐Wide Assessment of Shared Genetic Architecture Between Rheumatoid Arthritis and Cardiovascular Diseases

Background Patients with rheumatoid arthritis (RA) have a 2‐ to 10‐fold increased risk of cardiovascular disease (CVD), but the biological mechanisms and existence of causality underlying such associations remain to be investigated. We aimed to investigate the genetic associations and underlying mec...

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Autori principali:	Yanjun Guo, Wonil Chung, Zhilei Shan, Zhaozhong Zhu, Karen H. Costenbader, Liming Liang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wiley 2023-11-01
Serie:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Soggetti:	cardiovascular disease genetic correlation Mendelian randomization rheumatoid arthritis shared pathogenesis
Accesso online:	https://www.ahajournals.org/doi/10.1161/JAHA.123.030211
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