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Protein Folding Activity of the Ribosome (PFAR) –– A Target for Antiprion Compounds

Prion diseases are fatal neurodegenerative diseases affecting mammals. Prions are misfolded amyloid aggregates of the prion protein (PrP), which form when the alpha helical, soluble form of PrP converts to an aggregation-prone, beta sheet form. Thus, prions originate as protein folding problems. The...

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Príomhchruthaitheoirí: Debapriya Banerjee, Suparna Sanyal
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: MDPI AG 2014-10-01
Sraith:Viruses
Ábhair:
Rochtain ar líne:http://www.mdpi.com/1999-4915/6/10/3907
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