Ribosomal Dysfunction Is a Common Pathomechanism in Different Forms of Trichothiodystrophy

Mutations in a broad variety of genes can provoke the severe childhood disorder trichothiodystrophy (TTD) that is classified as a DNA repair disease or a transcription syndrome of RNA polymerase II. In an attempt to identify the common underlying pathomechanism of TTD we performed a knockout/knockdo...

Popoln opis

Bibliografske podrobnosti

Principais autores:	Gaojie Zhu, Fatima Khalid, Danhui Zhang, Zhouli Cao, Pallab Maity, Hans A. Kestler, Donata Orioli, Karin Scharffetter-Kochanek, Sebastian Iben
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2023-07-01
Serija:	Cells
Teme:	ribosome trichothiodystrophy translational infidelity loss of proteostasis
Online dostop:	https://www.mdpi.com/2073-4409/12/14/1877
Oznake:	Označite Brez oznak, prvi označite!