Anti-DENV IgE correlates with dengue severity and triggers FcεRI-dependent basophil activation inhibited by Omalizumab
Abstract Severe dengue, marked by plasma leakage, is often linked to secondary heterotypic dengue virus (DENV) infection. While mast cells and basophils contribute to dengue pathogenesis, the role of anti-DENV IgE remains unclear. Here, we investigated whether anti-DENV IgE promotes FcεRI-dependent...
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| Materiálatiipa: | Artigo |
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Nature Portfolio
2026-03-01
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| Ráidu: | Scientific Reports |
| Fáttát: | |
| Liŋkkat: | https://doi.org/10.1038/s41598-026-43199-z |
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