Development of tau phosphorylation-targeting therapies for the treatment of neurodegenerative diseases
Hyperphosphorylation of microtubule-associated protein tau is a major driver in the etiology of multiple neurodegenerative diseases, such as Alzheimer’s disease (AD) and other tauopathies. Intracellular accumulation of hyperphosphorylated tau (pTau) decreases microtubule stability, induces protein a...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
KeAi Communications Co., Ltd.
2024-12-01
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| coleção: | Medicine Plus |
| Assuntos: | |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S2950347724000562 |
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