Abietic acid protects cardiomyocytes from doxorubicin-induced apoptosis by modulating PI3K/Akt-mediated mitochondrial apoptosis
Doxorubicin (DOX) is a potent chemotherapeutic agent, but its clinical utility is severely compromised by dose-dependent, irreversible cardiotoxicity. There is an urgent need to develop novel drugs or therapeutic strategies to reduce DOX-induced cardiotoxicity. Abietic acid (AA), a natural product,...
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| Główni autorzy: | , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Elsevier
2026-06-01
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| Seria: | Pharmacological Research - Modern Chinese Medicine |
| Hasła przedmiotowe: | |
| Dostęp online: | http://www.sciencedirect.com/science/article/pii/S2667142526000643 |
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