The methyl donor S-adenosyl methionine reverses the DNA methylation signature of chronic neuropathic pain in mouse frontal cortex
Introduction:. Chronic pain is associated with persistent but reversible structural and functional changes in the prefrontal cortex (PFC). This stable yet malleable plasticity implicates epigenetic mechanisms, including DNA methylation, as a potential mediator of chronic pain–induced cortical pathol...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Wolters Kluwer
2021-08-01
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| Col·lecció: | PAIN Reports |
| Accés en línia: | http://journals.lww.com/painrpts/fulltext/10.1097/PR9.0000000000000944 |
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