The methyl donor S-adenosyl methionine reverses the DNA methylation signature of chronic neuropathic pain in mouse frontal cortex
Introduction:. Chronic pain is associated with persistent but reversible structural and functional changes in the prefrontal cortex (PFC). This stable yet malleable plasticity implicates epigenetic mechanisms, including DNA methylation, as a potential mediator of chronic pain–induced cortical pathol...
Gespeichert in:
| Hauptverfasser: | , , , , , , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Wolters Kluwer
2021-08-01
|
| Schriftenreihe: | PAIN Reports |
| Online-Zugang: | http://journals.lww.com/painrpts/fulltext/10.1097/PR9.0000000000000944 |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|