Treatment of calcific arterial disease via enhancement of autophagy using GSK343

Summary: Vascular calcification is a hallmark of atherosclerotic disease and serves as a strong predictor and risk factor for cardiovascular events. Growing evidence suggests that autophagy may play a protective role in early atherosclerosis. The precise effects of autophagy on VSMC-mediated calcifi...

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Bibliografske podrobnosti

Principais autores:	Christian L. Lino Cardenas, Wanlin Jiang, Lova P. Kajuluri, Kuldeep Singh, Katrina Ostrom, Rebecca Li, Francois Cherbonneau, Sophie Boerboom, Claire Birchenough, Kangsan Roh, Elizabeth L. Chou, Zarbafian Shahrooz, Christopher Nicholson, Adam L. Johnson, Sujin Lee, Fumito Ichinose, Donald B. Bloch, Sagar Nigwekar, Patrick T. Ellinor, Patricia Musolino, Mark E. Lindsay, Zhixun Dou, Clint L. Miller, Rajeev Malhotra
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2023-11-01
Serija:	iScience
Teme:	Cardiovascular medicine Human Genetics Molecular physiology
Online dostop:	http://www.sciencedirect.com/science/article/pii/S2589004223024379
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