Treatment of calcific arterial disease via enhancement of autophagy using GSK343

Summary: Vascular calcification is a hallmark of atherosclerotic disease and serves as a strong predictor and risk factor for cardiovascular events. Growing evidence suggests that autophagy may play a protective role in early atherosclerosis. The precise effects of autophagy on VSMC-mediated calcifi...

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Detalhes bibliográficos

Principais autores:	Christian L. Lino Cardenas, Wanlin Jiang, Lova P. Kajuluri, Kuldeep Singh, Katrina Ostrom, Rebecca Li, Francois Cherbonneau, Sophie Boerboom, Claire Birchenough, Kangsan Roh, Elizabeth L. Chou, Zarbafian Shahrooz, Christopher Nicholson, Adam L. Johnson, Sujin Lee, Fumito Ichinose, Donald B. Bloch, Sagar Nigwekar, Patrick T. Ellinor, Patricia Musolino, Mark E. Lindsay, Zhixun Dou, Clint L. Miller, Rajeev Malhotra
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2023-11-01
coleção:	iScience
Assuntos:	Cardiovascular medicine Human Genetics Molecular physiology
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2589004223024379
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