Multikinase Abl/DDR/Src Inhibition Produces Optimal Effects for Tyrosine Kinase Inhibition in Neurodegeneration

Abstract Background and objectives Inhibition of Abelson (Abl) tyrosine kinase as a therapeutic target has been gaining attention in neurodegeneration. Post-mortem Alzheimer’s and Parkinson’s disease brains show that the levels of several other tyrosine kinases, including Discoidin Domain Receptors...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Alan J. Fowler, Michaeline Hebron, Alexander A. Missner, Ruchong Wang, Xiaokong Gao, Bahjat T. Kurd-Misto, Xiaoguang Liu, Charbel E.-H. Moussa
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Adis, Springer Healthcare 2019-03-01
Schriftenreihe:	Drugs in R&D
Online-Zugang:	http://link.springer.com/article/10.1007/s40268-019-0266-z
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