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Two Sides of the Same Coin: Protein Kinase C γ in Cancer and Neurodegeneration

Protein kinase C (PKC) isozymes transduce myriad signals within the cell in response to the generation of second messengers from membrane phospholipids. The conventional isozyme PKCγ reversibly binds Ca2+ and diacylglycerol, which leads to an open, active conformation. PKCγ expression is typically r...

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Hlavní autoři: Caila A. Pilo, Alexandra C. Newton
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2022-06-01
Edice:Frontiers in Cell and Developmental Biology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fcell.2022.929510/full
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