Two Sides of the Same Coin: Protein Kinase C γ in Cancer and Neurodegeneration
Protein kinase C (PKC) isozymes transduce myriad signals within the cell in response to the generation of second messengers from membrane phospholipids. The conventional isozyme PKCγ reversibly binds Ca2+ and diacylglycerol, which leads to an open, active conformation. PKCγ expression is typically r...
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| Principais autores: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2022-06-01
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| Serier: | Frontiers in Cell and Developmental Biology |
| Fag: | |
| Online adgang: | https://www.frontiersin.org/articles/10.3389/fcell.2022.929510/full |
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