Activated Peyer′s patch B cells sample antigen directly from M cells in the subepithelial dome

Gut lumen antigens must be continuously sampled by the immune system to maintain proper immune homeostasis. Here the authors show that activated CCR6+CCR1+GL7- gut B cells retrieve lumen antigens from specialized M cells and transfer them across the subepithelial dome in the Peyer’s patch to contrib...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Rathan Joy Komban, Anneli Strömberg, Adi Biram, Jakob Cervin, Cristina Lebrero-Fernández, Neil Mabbott, Ulf Yrlid, Ziv Shulman, Mats Bemark, Nils Lycke
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2019-06-01
coleção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-019-10144-w
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!