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IL-4-Producing Vγ1+/Vδ6+ γδ T Cells Sustain Germinal Center Reactions in Peyer’s Patches of Mice

The mucosal immune system is the first line of defense against pathogens. Germinal centers (GCs) in the Peyer’s patches (PPs) of the small intestine are constantly generated through stimulation of the microbiota. In this study, we investigated the role of γδ T cells in the GC reactions in PPs. Most...

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Furkejuvvon:
Váldodahkkit: Leon Ullrich, Yvonne Lueder, Anna-Lena Juergens, Anneke Wilharm, Joana Barros-Martins, Anja Bubke, Abdi Demera, Koichi Ikuta, Gwendolyn Elena Patzer, Anika Janssen, Inga Sandrock, Immo Prinz, Francesca Rampoldi
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Frontiers Media S.A. 2021-11-01
Ráidu:Frontiers in Immunology
Fáttát:
germinal center
Peyer’s patches
γδ T cells
Vγ1+ T cells
IL-4
IgA
Liŋkkat:https://www.frontiersin.org/articles/10.3389/fimmu.2021.729607/full
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