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NLRP3 Inflammasome as a Molecular Marker in Diabetic Cardiomyopathy

Diabetic cardiomyopathy (DCM), a common consequence of longstanding diabetes mellitus, is initiated by death of cardiomyocyte. Hyperglycemia-induced reactive oxygen species (ROS) overproduction is a major contributor of the chronic low-grade inflammation that characterizes as the DCM. ROS may promot...

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Principais autores: Beibei Luo, Feng Huang, Yanli Liu, Yiying Liang, Zhe Wei, Honghong Ke, Zhiyu Zeng, Weiqiang Huang, Yan He
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017-07-01
coleção:Frontiers in Physiology
Assuntos:
NLRP3 inflammasome
thioredoxin interacting/inhibiting protein
pyroptosis
inflammation
diabetic cardiomyopathy
Acesso em linha:http://journal.frontiersin.org/article/10.3389/fphys.2017.00519/full
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