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CMKLR1 senses chemerin/resolvin E1 to control adipose thermogenesis and modulate metabolic homeostasis

Induction of beige fat for thermogenesis is a potential therapy to improve homeostasis against obesity. β3-adrenoceptor (β3-AR), a type of G protein-coupled receptor (GPCR), is believed to mediate the thermogenesis of brown fat in mice. However, β3-AR has low expression in human adipose tissue, prec...

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Principais autores: Zewei Zhao, Siqi Liu, Bingxiu Qian, Lin Zhou, Jianglin Shi, Junxi Liu, Lin Xu, Zhonghan Yang
Formato: Artigo
Idioma:Inglês
Publicado em: KeAi Communications Co. Ltd. 2024-05-01
coleção:Fundamental Research
Assuntos:
Obesity
Insulin resistance
Thermogenesis
CMKLR1
Resolvin E1
Chemerin
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2667325822002837
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