Case Report: A Multi-Peptide Vaccine Targeting Individual Somatic Mutations Induces Tumor Infiltration of Neoantigen-Specific T Cells in a Patient with Metastatic Colorectal Cancer

Background/Objectives: Fully personalized peptide vaccines targeting tumor-specific mutations are a promising treatment option for patients in an adjuvant but also advanced/metastatic disease situation in addition to non-personalized standard therapies. Here, we report a patient’s case with advanced...

Повний опис

Бібліографічні деталі

Автори:	Armin Rabsteyn, Henning Zelba, Borong Shao, Lisa Oenning, Christina Kyzirakos, Simone Kayser, Tabea Riedlinger, Johannes Harter, Magdalena Feldhahn, Dirk Hadaschik, Florian Battke, Veit Scheble, Alfred Königsrainer, Saskia Biskup
Формат:	Artigo
Мова:	Inglês
Опубліковано:	MDPI AG 2025-09-01
Серія:	Vaccines
Предмети:	personalized peptide vaccination metastatic colorectal cancer tumor-infiltrating lymphocytes neoantigens TCRβ sequencing
Онлайн доступ:	https://www.mdpi.com/2076-393X/13/9/960
Теги:	Додати тег Немає тегів, Будьте першим, хто поставить тег для цього запису!