Caloric Restriction Mimetic Hydroxycitrate Mitigates Acute Nephrotoxicity via Autophagy Activation and Oxidative Stress Reduction

Drug-induced nephrotoxicity is a leading cause of acute kidney injury (AKI) and subsequent chronic kidney disease. Nephrotoxicity often develops as a consequence of treatment with commonly prescribed aminoglycoside antibiotics, and remains a significant clinical challenge. One approach to treating A...

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Principais autores:	Xinyu Liao, Nadezda V. Andrianova, Ljubava D. Zorova, Anna A. Brezgunova, Kseniia S. Cherkesova, Marina I. Buyan, Dmitry S. Semenovich, Alexandra A. Dalina, Irina B. Pevzner, Juan Jin, Yunguang Wang, Egor Y. Plotnikov
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	MDPI AG 2026-04-01
סדרה:	Biomolecules
נושאים:	caloric restriction caloric restriction mimetics acute kidney injury inflammation autophagy mitochondria
גישה מקוונת:	https://www.mdpi.com/2218-273X/16/4/538
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