Caloric Restriction Mimetic Hydroxycitrate Mitigates Acute Nephrotoxicity via Autophagy Activation and Oxidative Stress Reduction

Drug-induced nephrotoxicity is a leading cause of acute kidney injury (AKI) and subsequent chronic kidney disease. Nephrotoxicity often develops as a consequence of treatment with commonly prescribed aminoglycoside antibiotics, and remains a significant clinical challenge. One approach to treating A...

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Principais autores:	Xinyu Liao, Nadezda V. Andrianova, Ljubava D. Zorova, Anna A. Brezgunova, Kseniia S. Cherkesova, Marina I. Buyan, Dmitry S. Semenovich, Alexandra A. Dalina, Irina B. Pevzner, Juan Jin, Yunguang Wang, Egor Y. Plotnikov
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2026-04-01
Serija:	Biomolecules
Teme:	caloric restriction caloric restriction mimetics acute kidney injury inflammation autophagy mitochondria
Online dostop:	https://www.mdpi.com/2218-273X/16/4/538
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