New functions of Ctf18-RFC in preserving genome stability outside its role in sister chromatid cohesion.
Expansion of DNA trinucleotide repeats causes at least 15 hereditary neurological diseases, and these repeats also undergo contraction and fragility. Current models to explain this genetic instability invoke erroneous DNA repair or aberrant replication. Here we show that CAG/CTG tracts are stabilize...
Na minha lista:
| Principais autores: | , , , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science (PLoS)
2011-02-01
|
| Serier: | PLoS Genetics |
| Online adgang: | http://europepmc.org/articles/PMC3037408?pdf=render |
| Tags: |
Ingen Tags, Vær først til at tagge denne postø!
|