Locus coeruleus integrity correlates with inhibitory functions of the fronto-subthalamic ‘hyperdirect’ pathway in Parkinson’s disease

A long-running debate concerns whether dopamine or noradrenaline deficiency drives response disinhibition in Parkinson’s disease (PD). This study aimed to investigate whether damage to the locus coeruleus (LC) or substantia nigra (SN) might impact inhibitory functions of the fronto-subthalamic hyper...

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Autors principals:	Biman Xu, Tingting He, Yuan Lu, Jia Jia, Barbara J. Sahakian, Trevor W. Robbins, Lirong Jin, Zheng Ye
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2022-01-01
Col·lecció:	NeuroImage: Clinical
Matèries:	Locus coeruleus Fronto-subthalamic hyperdirect pathway Response inhibition Parkinson's disease Neuromelanin-sensitive MRI fMRI
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2213158222003412
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