Isocitrate dehydrogenases in physiology and cancer: biochemical and molecular insight
Abstract Isocitrate dehydrogenases play important roles in cellular metabolism and cancer. This review will discuss how the roles of isoforms 1 and 2 in normal cell and cancer metabolism are distinct from those of isoform 3. It will also explain why, unlike 1 and 2, mutations in isoform 3 in tumor a...
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| Autor principal: | |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BMC
2017-08-01
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| Col·lecció: | Cell & Bioscience |
| Matèries: | |
| Accés en línia: | http://link.springer.com/article/10.1186/s13578-017-0165-3 |
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