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Isocitrate Dehydrogenase Mutations in Glioma: From Basic Discovery to Therapeutics Development

Isocitrate dehydrogenase (IDH) is a key rate-limiting enzyme in the Krebs cycle that plays an important role in energy metabolism. In recent years, it has been found that IDH mutations are closely related to the occurrence and development of glioma, and it is a notable potential therapeutic target....

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Juan Huang, Jialong Yu, Lin Tu, Nanqu Huang, Hang Li, Yong Luo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2019-06-01
Sarja:Frontiers in Oncology
Aiheet:
Linkit:https://www.frontiersin.org/article/10.3389/fonc.2019.00506/full
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