Preservation of functionality, immunophenotype, and recovery of HIV RNA from PBMCs cryopreserved for more than 20 years

BackgroundMany research laboratories have long-term repositories of cryopreserved peripheral blood mononuclear cells (PBMC), which are costly to maintain but are of uncertain utility for immunological studies after decades in storage. This study investigated preservation of cell surface phenotypes a...

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Autori principali:	Wayne B. Dyer, Kazuo Suzuki, Angelique Levert, Mitchell Starr, Andrew R. Lloyd, John J. Zaunders
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2024-08-01
Serie:	Frontiers in Immunology
Soggetti:	cryopreservation biobank viability immunophenotyping HIV reactivation T cell subsets
Accesso online:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1382711/full
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