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Preservation of functionality, immunophenotype, and recovery of HIV RNA from PBMCs cryopreserved for more than 20 years

BackgroundMany research laboratories have long-term repositories of cryopreserved peripheral blood mononuclear cells (PBMC), which are costly to maintain but are of uncertain utility for immunological studies after decades in storage. This study investigated preservation of cell surface phenotypes a...

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Glavni autori: Wayne B. Dyer, Kazuo Suzuki, Angelique Levert, Mitchell Starr, Andrew R. Lloyd, John J. Zaunders
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2024-08-01
Serija:Frontiers in Immunology
Teme:
cryopreservation
biobank
viability
immunophenotyping
HIV reactivation
T cell subsets
Online pristup:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1382711/full
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