Overexpression of active Aurora-C kinase results in cell transformation and tumour formation.
Aurora kinases belong to a conserved family of serine/threonine kinases key regulators of cell cycle progression. Aurora-A and Aurora-B are expressed in somatic cells and involved mainly in mitosis while Aurora-C is expressed during spermatogenesis and oogenesis and is involved in meiosis. Aurora-C...
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| Huvudupphov: | , , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
Public Library of Science (PLoS)
2011-01-01
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| Serie: | PLoS ONE |
| Länkar: | http://europepmc.org/articles/PMC3203144?pdf=render |
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