Identification of the Cysteine Protease Legumain as a Potential Chronic Hypoxia-Specific Multiple Myeloma Target Gene

Multiple myeloma (MM) is the second most common hematologic malignancy, which is characterized by clonal proliferation of neoplastic plasma cells in the bone marrow. This microenvironment is characterized by low oxygen levels (1–6% O₂), known as hypoxia. For MM cells, hypoxia is a physiol...

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Egile Nagusiak:	Ada-Sophia Clees, Verena Stolp, Björn Häupl, Dominik C. Fuhrmann, Frank Wempe, Marcel Seibert, Sarah Weber, Antje Banning, Ritva Tikkanen, Richard Williams, Bernhard Brüne, Hubert Serve, Frank Schnütgen, Ivana von Metzler, Nina Kurrle
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	MDPI AG 2022-01-01
Saila:	Cells
Gaiak:	multiple myeloma chronic hypoxia asparaginyl endopepdidase (AEP) legumain glycolysis
Sarrera elektronikoa:	https://www.mdpi.com/2073-4409/11/2/292
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