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The Protective Effect of (-)-Tetrahydroalstonine against OGD/R-Induced Neuronal Injury via Autophagy Regulation

Here, (-)-Tetrahydroalstonine (THA) was isolated from <i>Alstonia scholaris</i> and investigated for its neuroprotective effect towards oxygen–glucose deprivation/re-oxygenation (OGD/R)-induced neuronal damage. In this study, primary cortical neurons were pre-treated with THA and then subjected to O...

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Principais autores: Yumei Liao, Jun-Ya Wang, Yan Pan, Xueyi Zou, Chaoqun Wang, Yinghui Peng, Yun-Lin Ao, Mei Fong Lam, Xiaoshen Zhang, Xiao-Qi Zhang, Lei Shi, Shiqing Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2023-03-01
coleção:Molecules
Assuntos:
(-)-Tetrahydroalstonine
cerebral ischemia
OGD/R
autophagy
Akt/mTOR
Acesso em linha:https://www.mdpi.com/1420-3049/28/5/2370
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