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Aspirin alleviates pulmonary fibrosis through PI3K/AKT/mTOR-mediated autophagy pathway

Idiopathic pulmonary fibrosis (IPF) is a chronic and irreversible lung disease with limited therapeutic options. Aspirin can alleviate liver, kidney, and cardiac fibrosis. However, its role in lung fibrosis is unclear. This study aims to investigate the effects of aspirin on lung fibroblast differen...

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Principais autores: Jieting Peng, Xun Xiao, Shizhen Li, Xing Lyu, Hui Gong, Shengyu Tan, Lini Dong, Yan Y. Sanders, Xiangyu Zhang
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2023-02-01
Serier:Experimental Gerontology
Fag:
Aspirin
Idiopathic pulmonary fibrosis
Autophagy
PI3K/AKT/mTOR
Lung fibroblasts
Online adgang:http://www.sciencedirect.com/science/article/pii/S0531556523000062
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