An exploratory study investigating the effect of targeted hyperoxemia in a randomized controlled trial in a long-term resuscitated model of combined acute subdural hematoma and hemorrhagic shock in cardiovascular healthy pigs

Severe physical injuries and associated traumatic brain injury and/or hemorrhagic shock (HS) remain leading causes of death worldwide, aggravated by accompanying extensive inflammation. Retrospective clinical data indicated an association between mild hyperoxemia and improved survival and outcome. H...

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Hauptverfasser:	Thomas Datzmann, Franziska Münz, Andrea Hoffmann, Elena Moehrke, Martha Binzenhöfer, Michael Gröger, Thomas Kapapa, René Mathieu, Simon Mayer, Fabian Zink, Holger Gässler, Eva-Maria Wolfschmitt, Melanie Hogg, Tamara Merz, Enrico Calzia, Peter Radermacher, David Alexander Christian Messerer
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2023-04-01
Schriftenreihe:	Frontiers in Immunology
Schlagworte:	traumatic brain injury multimodal brain monitoring hemorrhagic shock radical oxygen species hyperoxemia
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1123196/full
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