Using UV–Vis Titration to Elucidate Novel Epigallocatechin Gallate (EGCG)-Induced Binding of the c-MYC G-Quadruplex
<b>Background/Objectives:</b> Aberrant expression of c-MYC drives aggressive cancers. A guanine-rich promoter sequence (Pu27) folds into a transcriptionally repressive G-quadruplex (G4). Epigallocatechin gallate (EGCG), the main green tea polyphenol, displays anticancer activity, but clear, easily r...
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| Format: | Artigo |
| Jezik: | Inglês |
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MDPI AG
2025-05-01
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| Serija: | Pharmaceuticals |
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| Online dostop: | https://www.mdpi.com/1424-8247/18/5/719 |
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