Using UV–Vis Titration to Elucidate Novel Epigallocatechin Gallate (EGCG)-Induced Binding of the c-MYC G-Quadruplex

<b>Background/Objectives:</b> Aberrant expression of c-MYC drives aggressive cancers. A guanine-rich promoter sequence (Pu27) folds into a transcriptionally repressive G-quadruplex (G4). Epigallocatechin gallate (EGCG), the main green tea polyphenol, displays anticancer activity, but clear, easily r...

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第一著者:	Justin Tang
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2025-05-01
シリーズ:	Pharmaceuticals
主題:	G-quadruplex c-MYC Epigallocatechin gallate (EGCG) polyphenol DNA binding UV–Vis spectroscopy
オンライン･アクセス:	https://www.mdpi.com/1424-8247/18/5/719
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