Functional compartmentalization of hepatic mitochondrial subpopulations during MASH progression
Abstract The role of peridroplet mitochondria (PDM) in diseased liver, such as during the progression of metabolic dysfunction-associated steatohepatitis (MASH), remains unknown. We isolated hepatic cytoplasmic mitochondria (CM) and PDM from a mouse model of diet-induced MASLD/MASH to characterize t...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2025-02-01
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| Colecção: | Communications Biology |
| Acesso em linha: | https://doi.org/10.1038/s42003-025-07713-9 |
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