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Synthesis, Biological Evaluation and Molecular Docking Studies of Ferrocene Derivatives Coupling with N-heterocyclic on Human Breast Cancer

A series of heterocyclic ferrocene derivatives (Fc1–Fc18) was designed and synthesized. The eight representative target compounds were evaluated for their antitumor activities against human breast cancer (MCF-7) cells using MTT assay. Compounds Fc3, Fc11, Fc12, and Fc17 inhibited MCF-7 cells at IC50...

Ausführliche Beschreibung

Gespeichert in:
Bibliografische Detailangaben
Hauptverfasser: Wu Yunlong, Yao Zhiyi
Format: Artigo
Sprache:Inglês
Veröffentlicht: EDP Sciences 2015-01-01
Schriftenreihe:MATEC Web of Conferences
Schlagworte:
Online-Zugang:http://dx.doi.org/10.1051/matecconf/20152205001
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