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Synthesis, Biological Evaluation and Molecular Docking Studies of Ferrocene Derivatives Coupling with N-heterocyclic on Human Breast Cancer

A series of heterocyclic ferrocene derivatives (Fc1–Fc18) was designed and synthesized. The eight representative target compounds were evaluated for their antitumor activities against human breast cancer (MCF-7) cells using MTT assay. Compounds Fc3, Fc11, Fc12, and Fc17 inhibited MCF-7 cells at IC50...

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Detalhes bibliográficos
Principais autores: Wu Yunlong, Yao Zhiyi
Formato: Artigo
Idioma:Inglês
Publicado em: EDP Sciences 2015-01-01
coleção:MATEC Web of Conferences
Assuntos:
Acesso em linha:http://dx.doi.org/10.1051/matecconf/20152205001
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