GRK6 palmitoylation dictates triple-negative breast cancer metastasis via recruiting the β-Arrestin 2/MAPKs/NF-κB signaling axis

Abstract Background Triple negative breast cancer (TNBC) belongs to the worst prognosis of breast cancer subtype probably because of distant metastasis to other organs, e.g. lungs. However, the mechanism underlying TNBC metastasis remains largely unknown. Methods Bioinformatics analysis was conducte...

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Autori principali:	Wen-Ke Wang, Hui-Yu Lin, Che-Hsuan Lin, Hsun-Hua Lee, Yen-Lin Chen, Yu-Hsien Kent Lin, Hui-Wen Chiu, Shry-Ming Sheen-Chen, Yuan-Feng Lin
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2024-12-01
Serie:	Breast Cancer Research
Soggetti:	Triple-negative breast cancer Metastasis GRK6 β-Arrestin 2 MAPKs NF-κB
Accesso online:	https://doi.org/10.1186/s13058-024-01953-z
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