Endothelial APC/PAR1 distinctly regulates cytokine-induced pro-inflammatory VCAM-1 expression

Introduction: Dysfunction of the endothelium impairs its’ protective role and promotes inflammation and progression of vascular diseases. Activated Protein C (APC) elicits endothelial cytoprotective responses including barrier stabilization, anti-inflammatory and anti-apoptotic responses through the...

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書誌詳細

主要な著者:	Cierra A. Birch, Helen Wedegaertner, Lennis B. Orduña-Castillo, Monica L. Gonzalez Ramirez, Huaping Qin, JoAnn Trejo
フォーマット:	Artigo
言語:	Inglês
出版事項:	Frontiers Media S.A. 2023-08-01
シリーズ:	Frontiers in Molecular Biosciences
主題:	GPCR cytoprotection GRK TNF-α thrombin
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fmolb.2023.1211597/full
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