Active CNS delivery of oxycodone in healthy and endotoxemic pigs
Abstract Background The primary objective of this study was to advance our understanding of active drug uptake at brain barriers in higher species than rodents, by examining oxycodone brain concentrations in pigs. Methods This was investigated by a microdialysis study in healthy and endotoxemic cond...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BMC
2024-10-01
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| Edice: | Fluids and Barriers of the CNS |
| Témata: | |
| On-line přístup: | https://doi.org/10.1186/s12987-024-00583-z |
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