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Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites

Current strategies for regulatory control of gene expression are orthogonal to the host organism mechanisms. Here the authors demonstrate an RNA aptamer controlled system integrated into native regulatory pathways in the parasite Plasmodium falciparum.

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Bibliografische Detailangaben
Hauptverfasser: Suresh M. Ganesan, Alejandra Falla, Stephen J. Goldfless, Armiyaw S. Nasamu, Jacquin C. Niles
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2016-03-01
Schriftenreihe:Nature Communications
Online-Zugang:https://doi.org/10.1038/ncomms10727
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