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Selective expression of variant surface antigens enables Plasmodium falciparum to evade immune clearance in vivo

During the erythrocyte (RBC) stage of P. falciparum infection variant surface antigens (VSAs) such as PfEMP1s and RIFINs expressed on RBCs are important for infection and evasion of host innate immune system. Here, Chew et al. use a NSG mouse model, which is deficient in B, T and NK cells but retain...

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主要な著者: Marvin Chew, Weijian Ye, Radoslaw Igor Omelianczyk, Charisse Flerida Pasaje, Regina Hoo, Qingfeng Chen, Jacquin C. Niles, Jianzhu Chen, Peter Preiser
フォーマット: Artigo
言語:Inglês
出版事項: Nature Portfolio 2022-07-01
シリーズ:Nature Communications
オンライン・アクセス:https://doi.org/10.1038/s41467-022-31741-2
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