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Inhibition of Plasmodium falciparum Hsp70-Hop partnership by 2-phenylthynesulfonamide

Plasmodium falciparum Hsp70-1 (PfHsp70-1; PF3D7_0818900) and PfHsp90 (PF3D7_0708400) are essential cytosol localized chaperones of the malaria parasite. The two chaperones form a functional complex via the adaptor protein, Hsp90-Hsp70 organizing protein (PfHop [PF3D7_1434300]), which modulates the i...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Tshifhiwa Muthelo, Vhahangwele Mulaudzi, Munei Netshishivhe, Tendamudzimu Harmfree Dongola, Michelle Kok, Stanley Makumire, Marianne de Villiers, Adélle Burger, Tawanda Zininga, Addmore Shonhai
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2022-09-01
Rangatū:Frontiers in Molecular Biosciences
Ngā marau:
Urunga tuihono:https://www.frontiersin.org/articles/10.3389/fmolb.2022.947203/full
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