Comprehensive benchmarking of methods for mutation calling in circulating tumor DNA
Abstract Detection of somatic mutations in cell-free DNA (cfDNA) is challenging due to low variant allele frequencies and extensive DNA degradation. Here we develop a benchmarking strategy using longitudinal patient-matched cfDNA samples from individuals with colorectal and breast cancer. Samples wi...
Збережено в:
| Автори: | , , , , , , , , , , , |
|---|---|
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Nature Portfolio
2025-12-01
|
| Серія: | Nature Communications |
| Онлайн доступ: | https://doi.org/10.1038/s41467-025-67842-x |
| Теги: |
Немає тегів, Будьте першим, хто поставить тег для цього запису!
|