PUREE: accurate pan-cancer tumor purity estimation from gene expression data
Abstract Tumors are complex masses composed of malignant and non-malignant cells. Variation in tumor purity (proportion of cancer cells in a sample) can both confound integrative analysis and enable studies of tumor heterogeneity. Here we developed PUREE, which uses a weakly supervised learning appr...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Portfolio
2023-04-01
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| Serie: | Communications Biology |
| Accesso online: | https://doi.org/10.1038/s42003-023-04764-8 |
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