Murine gamma-herpesvirus 68 hijacks MAVS and IKKbeta to initiate lytic replication.
Upon viral infection, the mitochondrial antiviral signaling (MAVS)-IKKbeta pathway is activated to restrict viral replication. Manipulation of immune signaling events by pathogens has been an outstanding theme of host-pathogen interaction. Here we report that the loss of MAVS or IKKbeta impaired the...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science (PLoS)
2010-07-01
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| Seri Bilgileri: | PLoS Pathogens |
| Online Erişim: | https://doi.org/10.1371/journal.ppat.1001001 |
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