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Murine gamma-herpesvirus 68 hijacks MAVS and IKKbeta to initiate lytic replication.

Upon viral infection, the mitochondrial antiviral signaling (MAVS)-IKKbeta pathway is activated to restrict viral replication. Manipulation of immune signaling events by pathogens has been an outstanding theme of host-pathogen interaction. Here we report that the loss of MAVS or IKKbeta impaired the...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Xiaonan Dong, Hao Feng, Qinmiao Sun, Haiyan Li, Ting-Ting Wu, Ren Sun, Scott A Tibbetts, Zhijian J Chen, Pinghui Feng
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Public Library of Science (PLoS) 2010-07-01
Rangatū:PLoS Pathogens
Urunga tuihono:https://doi.org/10.1371/journal.ppat.1001001
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